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Author Kreiborg S, Dahl E. Department of Pediatric Dentistry, School of Dentistry, Faculty of Health Sciences, University of Copenhagen, Denmark.
Source Am J Med Genet 1993 Oct 1;47(5):753-60
Abstract Using longitudinal roentgencephalometry, we studied craniofacial growth in two children with mandibulofacial dysostosis. In one child, data were supplemented by three-dimensional reconstructions of CT scans and stereolithographic models of the craniofacial skeleton. Progressive basilar kyphosis was found in both children, the hypothesized caused being bending of the cranial base at the level of the sphenofrontal suture. Such bending acting in concert with abnormal growth of the mandible led to impairment of the airway. We advocate careful monitoring of craniofacial growth and respiratory function in mandibulofacial dysostosis from birth through adolescence. (Auth abstract)XX