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Author Mizukami, Yoshiaki. Rajniak, Daniel. Nishimura, Masatoshi. Institution Sankyo Co, Ltd, Tokyo, Jpn
Source Proceedings of the IEEE Micro Electro Mechanical Systems (Mems). p 751-756.
Abstract We have fabricated an integrated micro-electrophoretic chip by implementing an acrylic microfluidic channel directly on top of a photosensor array using a new micro-fabrication process. The cross section of the microchannel is 100 mu m high multiplied by 100 mu m wide, and the effective length is 4.5 cm. The photosensor consists of 147 multiplied by 147 pixels, each measuring 39 mu m multiplied by 39 mu m. The integrated microchip is able to detect electrophoretic signals in real time along the whole microchannel as a two-dimensional image. The microfabrication process named `stereolithography with double controlled surface (SD method)' has been newly proposed in order to realize a highly transparent micro-channel with a smooth surface without assembly processes such as bonding of two plates. The accuracy of fabrication is within 5% of the design values. We have also evaluated the performance of the fabricated microchip and confirmed its functionality. After a sample (Blue Dextran) was injected into the microchannel, significant values of absorbance were obtained from the photosensor along the whole microchannel. The absorbance was proportional to the concentration of Blue Dextran. (Auth abstract) [References: 10] XX